Commentary for Pesachim 107:15

דורשי חמורות היו אומרים ענה פסול היה לפיכך הביא פסול לעולם שנאמר (בראשית לו, כ) אלה בני שעיר החורי וכתיב אלה בני צבעון ואיה וענה אלא מלמד שבא צבעון על אמו והוליד ממנה ענה

R'Simeon B'Gamaliel said: The mule came into existence in the days of Anah, for it is said, This is the Anah who found the mules<span class="x" onmousemove="('comment',' E.V. 'hot Springs'.');">³⁸</span> in the wilderness.<span class="x" onmousemove="('comment',' Gen. XXXVI, 24. ,urunv harus rnuv');">³⁹</span> Those who interpret symbolically<span class="x" onmousemove="('comment',' Lit., 'those who interpret (Scripture) as jewels', i.e., as ethical teachings. Levi connects the phrase with a beautiful and graceful gazelle, i.e., those who teach with charming and graceful interpretations.');">⁴⁰</span> used to say: Anah was unfit,<span class="x" onmousemove="('comment',' Pasul, i.e., the issue of an incestuous union.');">⁴¹</span>

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