Reference for Avodah Zarah 47:13
א"ה אמאי דמיה יקרין הואיל ושתי שערות פוסלות בה ומאי שנא דידהו אמר רב כהנא במוחזקת
If that is so, why should [a red heifer] be so costly? Because even two hairs [of another color] disqualify her. Then why [use this means] on their [animals]? R. Kahana said: When it was assumed [to be of the breed that could form a red heifer].
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