Reference for Avodah Zarah 93:17

כי תיבעי לך אליבא דמ"ד עיקר שירה בפה בסומי קלא בעלמא הוא ומייתינן או דלמא אפילו הכי אסיר תיקו

but the question does arise according to him who says that the main aspect of [Temple] music is with the mouth. Is, then, the purpose [of the instrument] only to sweeten the sound and we may use these [materials], or perhaps even then it is prohibited? The question remains unanswered.

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