Reference for Gittin 112:12

איכא דאמרי קבורים ממש דאפילו מילי דמטמרן איגלייא להון

and physicians to heal R. Zadok. R. Joseph, or some say R. Akiba, applied to him the verse, '[God] turneth wise men backward and maketh their knowledge foolish'. He ought to have said to him; Let them [the Jews] off this time. He, however, thought that so much he would not grant, and so even a little would not be saved.

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