Talmud Bavli
Talmud Bavli

Responsa for Avodah Zarah 97:6

ר"א אומר אחר האחרון אני בא וחכ"א בין שנפל איסור לכתחלה ובין שנפל איסור לבסוף אינו אסור עד שיהא בו כדי לחמץ

R. Eliezer says: I follow whichever [leaven went into the dough] last. But the sages say: Whether the prohibited leaven fell in first or last, [the dough] is not prohibited unless it is of a sufficient quantity by itself to cause fermentation.

Teshuvot Maharam

Since vinegar is used in flavoring food, it does not lose its identity even when mixed with a substance more than 60 times its volume.
SOURCES: Pr. 100; Cr. 46 end; L. 368 end. Cf. Sefer Haparnes 22.
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