Responsa for Yevamot 209:19

שלחו ליה לאבוה דשמואל יבמה שרקקה דם תחלוץ לפי שאי אפשר לדם בלא צחצוח רוק

[The following ruling] was sent to Samuel's father: A sister-inlaw who spat blood shall perform <i>halizah</i>,<span class="x" onmousemove="('comment',' As in the case of ordinary spitting. she may not subsequently contract levirate marriage. ');">⁴⁶</span> because it is impossible that blood should not contain some diluted particles of spittle. An objection was raised: It might have been assumed that blood that issues from his<span class="x" onmousemove="('comment',' A man who hath an issue, cf. Lev. XV, 2. ');">⁴⁷</span>

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