Reference for Chullin 18:1

חוששין שמא במקום נקב נקב

one must apprehend that it was nibbling in a pre-existing hole!<span class="x" onmousemove="('comment',' I.e., , a hole made by a snake in which it deposited poison; the fruit is, therefore, prohibited to be eaten on account of this danger.');">¹</span>

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