Reference for Chullin 253:37

נהר פקודאה לוייך מגלימא שפירא דחזי עלך

When I came before R'Simeon the pious, [and related this to him,] he said to me: The Holy One, blessed be He, said: They have produced a new creature which I had not created into my world, I too will bring upon them a creature which I had not created in my world.<span class="x" onmousemove="('comment',' Sc. the 'arod whose bite is deadly; cf. Ber. 331.');">²⁴</span>

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