Reference for Chullin 66:22

ולוקמה כרבי עקיבא דאמר ידיו תחלות הויין

who also holds that hands can be unclean in the first degree? - Because it may be that R'Akiba says so<span class="x" onmousemove="('comment',' That hands can be unclean in the first degree.');">¹⁵</span>

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