Reference for Pesachim 41:3
אבל נפלה למאה חולין טמאין דברי הכל תרד ותטמא ואל יטמאנה ביד
It was taught likewise: If a cask [of clean terumah] was broken in the upper vat, and beneath it there is one hundred [times as much] unclean hullin. R'Eliezer concedes to R'Joshua that if he can save a rebi'ith thereof in purity he must save it, but if not, let it descend and be defiled, but he must not defile it with [hi own] hands.
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