פירוש על קידושין 109:3

This mishnah from Tractate Me’ilah teaches that misusing an animal dedicated to the Temple or a vessel from the Temple does not desacralize them. Thus no matter how many people use these items in a non-holy way, each person commits trespass. This shows that things that have intrinsic holiness, such as animals donated to be sacrifices, cannot be desacralized. This differs from things whose value was donated to the Temple. These do not have intrinsic holiness and can be redeemed.
In any case, this seems to prove that things with intrinsic holiness cannot be redeemed (i.e. desacralized), whereas in yesterday’s mishnah, about animals found near Jerusalem, we said they could be redeemed.