הלכה על ברכות 12:6

The designation of a place of prayer expresses the complete connection that we have with God. Everything else in the world can change, but one’s connection to God is the most permanent and stable reality and should therefore transpire at a fixed place. The Sages say: “Whoever sets a place to pray is helped by the God of Avraham, and his enemies fall to him” (Berakhot 6b, 7b; see Maharal, Netiv Ha-avoda, ch. 4).