Musar for Berakhot 12:6

ואם תלכו עמי קרי . We learn from here that a person must set aside a specific place for his Torah study and prayers, etc. He should not let this become a matter of coincidence, קרי.

Abraham suffered spiritually from having a foreskin. The foreskin may be perceived as an obstacle to receptivity of higher degrees of sanctity by the body. Only after Abraham became circumcised was he able to resume his spiritual ascent towards higher insights and a higher level of sanctity. His descendants after him achieved some permanent sanctity in space. Some of his descendants were not fit however, and, until Jacob, whose children were all loyal, no permanent site of holiness was established. When the Talmud Berachot 6b said that כל הקובע מקום לתפלתו אלוקי אברהם בעזרו, "Anyone who prays from a site permanently assigned for that purpose will enjoy the assistance of the G–d of Abraham," this is an allusion to the fact that Abraham was the first to establish sanctity of space on earth.

An important function of the six pillars which ensure this world's continued existence is that we, who perform the commandments which symbolise these six pillars, associate as closely as possible with the four supports. In metaphorical language: Since we have a tradition that G–d only has the four cubits of הלכה in this world, study and performance of the six pillars mentioned is equivalent to secluding oneself in the Tent of Torah. Our sages (Berachot 6b) have said that all our enemies will succumb if someone sets aside a special place for studying Torah.