Responsa for Berakhot 108:15
מי שחלה ונתרפא דכתיב אוילים מדרך פשעם ומעונותיהם יתענו כל אוכל תתעב נפשם וגו' ויזעקו אל ה' בצר להם וגו' ישלח דברו וירפאם וגו' יודו לה' חסדו
"The invalid who recovers" — whence have we this? For it is written, "Crazed because of the way of their transgression, and afflicted because of their iniquities, their soul abhorred all manner of food... They cried unto the Lord in their trouble... He sent His word and healed them...Let them give thanks unto the Lord for His mercy" (Ps. cvii. 17—21).
Shut min haShamayim
They responded to the first question: "Lift your hands to the sacred!" (Psalms 134:2) Namely, wash your hands whenever you want to speak sacred words or study Torah. "And bless God!" (ibid.) - with the blessing instituted for washing hands. As for the second question, they responded: Do you not know that four need to give thanks (Berachot 54b:12), and this includes one who was sick. And none are more sick than such a person [who relieves themself], as it says (Isaiah 51:14): "Quickly the crouching one is freed."2cf. Rashi on Isaiah 51:14
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